Searching low-energy conformations of two elastin sequences
نویسنده
چکیده
The three-dimensional structures of two common repeat motifs Val-Pro-Gly-Val-Gly and ValGly-Val-Pro-Gly-Val-Gly-Val-Pro of tropoelastin are investigated by using the multicanonical simulation procedure. By minimizing the energy structures along the trajectory the thermodynamically most stable low-energy microstates of the molecule are determined. The structural predictions are in good agreement with X-ray diffraction experiments.
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تاریخ انتشار 2004